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Chiral capillary electrophoresis with noncyclic oligo‐and polysaccharide chiral selectors

Identifieur interne : 002953 ( Main/Exploration ); précédent : 002952; suivant : 002954

Chiral capillary electrophoresis with noncyclic oligo‐and polysaccharide chiral selectors

Auteurs : Richard M. C. Sutton [États-Unis] ; Karen L. Sutton [États-Unis] ; Apryll M. Stalcup [États-Unis]

Source :

RBID : ISTEX:AC3F2ACB739FA7E09E19C18F1D4532AAAC1943F8

English descriptors

Abstract

A number of noncyclic oligo‐ and polysaccharides have been used as chiral additives in capillary electrophoresis (CE). This review offers a broad survey of the types of oligo‐ and polysaccharides which have been investigated and also some of the conditions developed for the enantioseparation of a wide range of drugs and other racemic compounds. Details of enantioseparation mechanisms are also discussed, in addition to some of the parameters required for optimization of the enantioresolution of chiral molecules.

Url:
DOI: 10.1002/elps.1150181220


Affiliations:


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Le document en format XML

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<term>Additive</term>
<term>Aminoglycosides</term>
<term>Analytes</term>
<term>Basic drugs</term>
<term>Biospecific activity</term>
<term>Buffer system</term>
<term>Capillary electrophoresis</term>
<term>Chiral</term>
<term>Chiral additive</term>
<term>Chiral additives</term>
<term>Chiral molecules</term>
<term>Chiral recognition</term>
<term>Chiral selector</term>
<term>Chiral selectors</term>
<term>Chondroitin</term>
<term>Chondroitin sulfate</term>
<term>Dextran</term>
<term>Dextran sulfate</term>
<term>Dextrans</term>
<term>Dextrin</term>
<term>Diltiazem</term>
<term>Enantiomer</term>
<term>Enantioresolution</term>
<term>Enantioresolved</term>
<term>Enantioseparation</term>
<term>Enantioseparations</term>
<term>Fradiomycin</term>
<term>Greater resolution</term>
<term>Helical structure</term>
<term>Heparin</term>
<term>Heparin concentration</term>
<term>Hydrophobic interactions</term>
<term>Ibuprofen</term>
<term>Kanamycin</term>
<term>Maltodextrins</term>
<term>Migration time</term>
<term>Migration times</term>
<term>Molecular mass</term>
<term>Nishi</term>
<term>Noncyclic</term>
<term>Noncyclic oligo</term>
<term>Oligo</term>
<term>Phosphate buffer</term>
<term>Phosphate buffer system</term>
<term>Polysaccharide</term>
<term>Polysaccharide chiral selectrors</term>
<term>Selector</term>
<term>Stalcup</term>
<term>Streptomycin</term>
<term>Sulfate</term>
<term>Sutton</term>
<term>Terabe</term>
<term>Trimetoquinol</term>
<term>Trimetoquinol isomer</term>
<term>Wide range</term>
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